The transformation mechanism of ofloxacin (OFL) by chlorine dioxide disinfection in water distribution system: kinetics, byproducts and toxicity

Abstract There is a research gap on the transformation of ofloxacin (OFL) in water supply systems under action ClO2. The degradation kinetics OFL different ClO2 concentrations, pH and pipe materials, formation intermediates, as well toxicity were first studied. results showed that PE deionized increased with increase concentration, reaction followed second-order kinetic model. removal rate was faster than pipe. tube positively correlated pH. In addition, efficiency pipes followed: cast iron > stainless steel detection intermediates cleavage piperazine groups main initial products process OFL. decarboxylation quinolone also detected. aquatic test by would water, therefore, decrease may not mean toxicity.